missense and nonsense mutations of p53 gene in patients with colorectal adenocarcinoma in isfahan, central iran
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چکیده
منابع مشابه
Missense and Nonsense Mutations of P53 Gene in Patients with Colorectal Adenocarcinoma in Isfahan, Central Iran
Dear Editor, The colorectal cancer is the forth prevalent cancer worldwide. The incidence and mortality of colorectal cancer (CRC) in men and women has been estimated more than 1.233 million cases and nearly 610000 deaths annually respectively It is also the forth prevalent cancer in Iran. The CRC occurrence is correlated with genetic and non-genetic factors such as missense and non-missense mu...
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Nuclear genetic mutations have been extensively investigated in solid tumors. However, the role of the mitochondrial genome remains uncertain. Since the metabolism of solid tumors is associated with aerobic glycolysis and high lactate production, tumors may have mitochondrial dysfunctions. Familial adenomatous polyposis (FAP) is a rare form of colorectal cancer and an autosomal dominant inheri...
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15 صفحه اولthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
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Introduction: Abortion is a common complication that refers to the early termination of pregnancy with the death of the fetus before the 20th week of pregnancy. Previous studies show that many genes are involved in this disease, including the CX3CR1 gene, which is one of the inflammatory response genes in the immune system. The pathogenicity of these variants was determined in this study using ...
متن کاملAnalysis of TP53 Codon 72 Polymorphism in Mucinous and Non-Mucinous Colorectal Adenocarcinoma in Isfahan, Iran
Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...
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عنوان ژورنال:
iranian red crescent medical journalجلد ۱۳، شماره ۳، صفحات ۲۱۵-۲۱۶
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